Ketamine Therapy in Scottsdale, AZ
Ketamine Treatment in Treatment Resistant Depression & Access to Rare 360 Degree Care
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Why IM Ketamine :
Many studies have found that ketamine introduced IM or IV can rapidly reduce symptoms of major depressive disorder (MDD) and treatment-resistant depression (TRD), often within 1–4 hours after administration. This is a significant breakthrough for individuals who have not responded to traditional antidepressants.
At One Psychiatry PLLC Dr DePalma administers Ketamine to patients intramuscularly to the deltoid muscle ( in normal speech , this is basically a shot of individually dosed Ketamine via the shoulder muscle).
Research indicates ketamine promotes brain-derived neurotrophic factor (BDNF) release and enhances synaptic connectivity. This may underlie its ability to help patients “shift out” of rigid, depressive, or trauma-driven thought patterns.
360 degree care:
Dr DePalma's training and experience as a fully Residency trained, Board Certified, Physician Psychiatrist (and ACLS trained)- who also offers Ketamine treatment - allows for a very rare full and comprehensive Psychiatric treatment experience that is almost impossible to find at the current time.
Dr. DePalma is prepared to manage not just your Ketamine Administration and treatment, but all of the profound Psychological Aspects associated with Ketamine treatment as well as managing your psychiatric symptoms AND medications. This allows for addressing all aspects in Ketamine treated patients of Treatment Resistant Depression , management issues in the context of Ketamine , Psychological navigation as well as relevant medical work up and evaluation when called for.
Also, unlike some "ketamine mills" and "drip dens" who leave patients in rooms (sometimes several patients in a room) to be checked up on periodically by minimally trained technicians, the Dr will be accessible at all times - even while you are in recliner during the quiet relaxation period of the session.
IMPORTANT:
*note that all new patients who desire ketamine treatment must first schedule and complete an Initial Evaluation with Dr DePalma.
(Not necessary for current patients of Dr DePalma)
*note that all new patients who desire ketamine treatment must first schedule and complete an Initial Evaluation with Dr DePalma.
(Not necessary for current patients of Dr DePalma)
IM Ketamine administration offers several advantages to oral and IV:
Why we currently do not offer oral/sublingual Ketamine treatment:
- Fast onset: Relief can begin within 10–15 minutes.
- Predictable absorption: Avoids variability of oral dosing.
- Convenience: No IV line required; less clinical infrastructure needed.
- Accessibility: Generally Lower cost and simpler logistics compared to infusions.
Why we currently do not offer oral/sublingual Ketamine treatment:
- Limited clinical trials: There are only a few studies and case series on sublingual use and most are small-scale low power studies. IM Ketamine administration on the other hand has robust clinical research evidence, well known pharmacokinetics and predictable bioavailability, greatly increasing the chances your treatment will be effective.
- Bioavailability of oral/sublingual is highly variable compared to IM/IV: Estimated at 15-30% depending on formulation, duration under the tounge and individual metabolism differences.
- Other: Existing Data is from unreliable sources and there are few standardized protocols causing dosage to vary widely among clinics.
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Summary of Evidence-Based Consensus
Treatment Format Number of Sessions Key Findings
Single infusion 1 Rapid, but often short-lived relief ( day(s) to week(s))
Repeated infusions 6 (over 3–4 weeks) Significantly higher and more durable response rates
Maintenance (optional) As needed (every 3–6 weeks or as needed) May prolong antidepressant effects in responders
*most often patients do maintenance "as needed" - if /when symptoms return or if triggered by stressors often going many weeks to months without maintenance
* some patients don't need any maintenance - each patient is unique
Treatment Format Number of Sessions Key Findings
Single infusion 1 Rapid, but often short-lived relief ( day(s) to week(s))
Repeated infusions 6 (over 3–4 weeks) Significantly higher and more durable response rates
Maintenance (optional) As needed (every 3–6 weeks or as needed) May prolong antidepressant effects in responders
*most often patients do maintenance "as needed" - if /when symptoms return or if triggered by stressors often going many weeks to months without maintenance
* some patients don't need any maintenance - each patient is unique
KETAMINE ASSISTED PSYCHOTHERAPY AT ONE PSYCHIATRY :
Typically 2 sessions are performed on new patients , after which time if they are responders all 6 sessions are completed within a 3 week period of time in order to complete the Induction series.
Dr. DePalma uses the following dynamic protocol of ketamine assisted therapy :
Typically 2 sessions are performed on new patients , after which time if they are responders all 6 sessions are completed within a 3 week period of time in order to complete the Induction series.
Dr. DePalma uses the following dynamic protocol of ketamine assisted therapy :
- IM Injection of individually dosed ketamine by Dr DePalma
- Period of relaxing music using profession grade stereo headphones in recliner
- Period of Psychotherapeutic processing / discussion of the experience.
- Assessment for discharge to prearrange travel arrangement.
Pricing:
Intake Evaluation: $325 (not required for current patients)
Cost of Ketamine Sessions:
Dr DePalma has been keeping the pricing per 90 minute session at a flat rate of $500 / session in an effort to make this option available to his patients who may benefit from this option * This includes cost of Ketamine and In session Psychotherapy/Processing
* All Treatment Sessions and Initial Evaluation are with ABPN board certified Physician Psychiatrist Dr. DePalma
Q: What is the first step in scheduling my Ketamine Treatment ?
A: The first step is scheduling an Initial Intake Evaluation Appointment using the "INITIAL INTAKE EVALUATION" button below.
Most patients wait and schedule the actual Ketamine Sessions and decide on treatment packages during or after this Initial Intake Evaluation Appointment. Or if you are a current patient just message Dr. DePalma through the Healthie portal indicating you'd like to discuss this treatment.
Alternatively, if you'd like to check to see which upcoming days of the week are available for your sessions, you can request an informational phone call using the request button below on this page and discuss this during that informational phone call.
Q: Is Ketamine Addictive?
A: When administered in a medical setting and at therapeutic doses, ketamine therapy is not considered addictive. In a controlled clinical environment—under the supervision of a licensed medical provider--the risk of developing dependence is extremely low. The doses used for treating depression, anxiety, or PTSD are much lower and given far less frequently than those associated with recreational or misuse patterns. Ketamine does have a potential for abuse when used repeatedly or in high, non-medical doses, such as those found in illicit settings. In the case of the high profile death of a Hollywood actor (M Perry) for example the concentrations found in his blood were on the order of 40-50 times ( notably buprenorphine was also present) higher than those used in psychiatric treatment.
Q: How is Dr. DePalma’s approach different?
He combines psychiatric expertise with Ketamine therapy for a fully integrated mental health treatment experience. Most Ketamine treatment in Phoenix and Scottdsale area is administered by technicians with minimal Psychiatric and medical training, allowing little if any interaction or supervision from a Physician Psychiatrist. It is Dr DePalma's belief that such organizations are doing a disservice in the long term to patients. This is why Dr DePalma administers and oversees all Ketamine Treatment sessions personally.
Q: Is Ketamine therapy safe?
A: Yes, when administered under medical supervision by a qualified ACLS certified healthcare professional like Dr. DePalma.
Q: What if I am currently on an antidepressant? Should I stay on it?
A: If you are currently on an oral antidepressant you feel is beneficial (even if partially) you may typically continue this medication regimen during treatment with exception of some medication types. The details of this can be addressed during the Initial Intake Evaluation or if you would like you may use the button below this section to request an informational phone call during which you can also ask questions regarding your medication (if it is the physician who calls you) or relay this question to him (if it is an assistant who calls you).
Q: Does insurance cover Ketamine therapy?
Most likely not; it’s best to check with your insurance provider however, despite the large body of evidence for psychiatric use, Ketamine is used “off label” for Psychiatric purposes at this time.
Q: What if I come to an Initial Intake Evaluation Appointment but I am told I am not a candidate for Ketamine Treatment for medical reasons or not meeting treatment resistant depression criteria?
A: In such a case you would be given the option to pursue other treatment options with Dr DePalma as recommended for you based on your medical/psychiatric status. And, if you decide you'd like to not pursue treatment options with Dr DePalma other than ketamine (but are not approved for it) in this case Dr DePalma will refund you a two thirds (2/3) refund ($200) thus you will have only paid $100 for the Drs time and evaluation in such case.
Q: Will I need to arrange transportation home from the Ketamine Therapy Sessions?
A: Yes, for safety reasons, patients must arrange a ride home from a responsible adult for each Ketamine Therapy Session. Although, this is not necessary for the Initial Evaluation Appointment.
Q: Are there any Zero Interest Financing options?
A: Yes - See Below in the "Financing" Section
Q: Will I need to stop my current medications?
Not necessarily—Dr. DePalma can manage your medications to ensure they complement your Ketamine therapy.
Q: Are HSA Cards Accepted?
A: Yes
Financing:
One Psychiatry is an Approved Provider with Advance Care which offers zero interest payment options.
This payment option is being made available by patient request though we do have reservations about patients taking on debt (zero interest or otherwise).
*We only currently endorse the zero credit payment option and do not endorse any other associated offers from this company such as "My Medical Funding" which does charge interest.
One Psychiatry is an Approved Provider with Advance Care which offers zero interest payment options.
This payment option is being made available by patient request though we do have reservations about patients taking on debt (zero interest or otherwise).
*We only currently endorse the zero credit payment option and do not endorse any other associated offers from this company such as "My Medical Funding" which does charge interest.
Phoenix & Scottsdale Ketamine Therapy – Expert Psychiatric Care by Dr. DePalma
Ketamine therapy has emerged as a groundbreaking treatment for individuals struggling with treatment-resistant depression and other severe mental health conditions. In the Phoenix and Scottsdale area, however, most Ketamine treatments are not administered by actual Psychiatrists. These professionals often cannot provide the full psychiatric care needed to address the complex mental health and emotional needs that accompany this treatment.
This is where Dr. DePalma stands apart. As a Board-Certified Physician Psychiatrist, he offers not just safe and effective Ketamine administration but also comprehensive psychiatric oversight—ensuring patients receive complete mental health support alongside their Ketamine therapy.
Why Choose Ketamine Therapy in Phoenix & Scottsdale
Ketamine therapy in Phoenix and Scottsdale provides hope for those who have tried traditional antidepressants without success. Unlike standard treatments that can take weeks to work, Ketamine often produces rapid improvement—sometimes within hours.
Patients in this region benefit from Dr. DePalma’s unique approach, which blends cutting-edge Ketamine protocols with in-depth psychiatric evaluation, medication management, and therapeutic guidance.
Meet Dr. DePalma – Board-Certified Psychiatrist
Expertise Beyond Most
Most providers focus solely on the medical administration of Ketamine. However, Dr. DePalma’s psychiatric expertise enables him to address comprehensive aspects of mental health conditions, ensuring a deeper, more personalized treatment experience.
Full-Spectrum Psychiatric & Medical Evaluation
Before starting Ketamine therapy, Dr. DePalma conducts a comprehensive medical and psychiatric evaluation and a review of your current medications. This ensures the treatment is tailored to your unique health needs.
Benefits of Ketamine Therapy for Treatment-Resistant Depression
Rapid Relief from Severe Depression
One of Ketamine’s most remarkable qualities is its ability to relieve severe depression in hours to days, rather than weeks.
Addressing Long-Standing Psychological Trauma
Ketamine has shown promise in helping patients confront and heal from deep-rooted emotional trauma, offering new perspectives and emotional clarity.
Comprehensive Psychiatric Care During Ketamine Treatment
Medication Management in the Context of Ketamine
Dr. DePalma carefully adjusts psychiatric medications as needed to work in harmony with Ketamine, ensuring maximum benefit and safety.
Psychological Support & Integration Therapy
Beyond the infusion, patients receive therapeutic support to integrate the emotional breakthroughs and insights gained during Ketamine sessions.
Safe & Monitored Medical Oversight
Your treatment is closely monitored for safety, side effects, and overall progress, giving you peace of mind.
The Ketamine Treatment Process at Dr. DePalma’s Clinic
Initial Consultation & Evaluation
The journey begins with a thorough discussion of your medical and mental health history.
Customized Treatment Plan
Based on your needs, Dr. DePalma designs a Ketamine protocol uniquely for you.
Follow-Up & Long-Term Support
After each session, you’ll have ongoing psychiatric check-ins to guide your recovery. Dr DePalma will also be there to manage ongoing medication management and psychiatric needs providing crucial continuity and comprehensive care.
Serving Scottsdale, Phoenix and Surrounding Communities
Dr. DePalma proudly serves patients from Scottsdale, Phoenix and nearby areas, offering compassionate, expert care that combines modern medicine with personalized psychiatric support.
Transformative Mental Health Care in Phoenix & Scottsdale & Phoenix
If you’re in the Scottsdale Phoenix area and struggling with treatment-resistant depression or trauma, Ketamine therapy under the guidance of Dr. DePalma offers a rare and comprehensive path to healing. With his expertise as a Board-Certified Psychiatrist, you’ll receive not only the benefits of Ketamine but also the full spectrum of psychiatric care you deserve.
Your mental health journey can start today—because lasting change is possible.
Ketamine therapy has emerged as a groundbreaking treatment for individuals struggling with treatment-resistant depression and other severe mental health conditions. In the Phoenix and Scottsdale area, however, most Ketamine treatments are not administered by actual Psychiatrists. These professionals often cannot provide the full psychiatric care needed to address the complex mental health and emotional needs that accompany this treatment.
This is where Dr. DePalma stands apart. As a Board-Certified Physician Psychiatrist, he offers not just safe and effective Ketamine administration but also comprehensive psychiatric oversight—ensuring patients receive complete mental health support alongside their Ketamine therapy.
Why Choose Ketamine Therapy in Phoenix & Scottsdale
Ketamine therapy in Phoenix and Scottsdale provides hope for those who have tried traditional antidepressants without success. Unlike standard treatments that can take weeks to work, Ketamine often produces rapid improvement—sometimes within hours.
Patients in this region benefit from Dr. DePalma’s unique approach, which blends cutting-edge Ketamine protocols with in-depth psychiatric evaluation, medication management, and therapeutic guidance.
Meet Dr. DePalma – Board-Certified Psychiatrist
Expertise Beyond Most
Most providers focus solely on the medical administration of Ketamine. However, Dr. DePalma’s psychiatric expertise enables him to address comprehensive aspects of mental health conditions, ensuring a deeper, more personalized treatment experience.
Full-Spectrum Psychiatric & Medical Evaluation
Before starting Ketamine therapy, Dr. DePalma conducts a comprehensive medical and psychiatric evaluation and a review of your current medications. This ensures the treatment is tailored to your unique health needs.
Benefits of Ketamine Therapy for Treatment-Resistant Depression
Rapid Relief from Severe Depression
One of Ketamine’s most remarkable qualities is its ability to relieve severe depression in hours to days, rather than weeks.
Addressing Long-Standing Psychological Trauma
Ketamine has shown promise in helping patients confront and heal from deep-rooted emotional trauma, offering new perspectives and emotional clarity.
Comprehensive Psychiatric Care During Ketamine Treatment
Medication Management in the Context of Ketamine
Dr. DePalma carefully adjusts psychiatric medications as needed to work in harmony with Ketamine, ensuring maximum benefit and safety.
Psychological Support & Integration Therapy
Beyond the infusion, patients receive therapeutic support to integrate the emotional breakthroughs and insights gained during Ketamine sessions.
Safe & Monitored Medical Oversight
Your treatment is closely monitored for safety, side effects, and overall progress, giving you peace of mind.
The Ketamine Treatment Process at Dr. DePalma’s Clinic
Initial Consultation & Evaluation
The journey begins with a thorough discussion of your medical and mental health history.
Customized Treatment Plan
Based on your needs, Dr. DePalma designs a Ketamine protocol uniquely for you.
Follow-Up & Long-Term Support
After each session, you’ll have ongoing psychiatric check-ins to guide your recovery. Dr DePalma will also be there to manage ongoing medication management and psychiatric needs providing crucial continuity and comprehensive care.
Serving Scottsdale, Phoenix and Surrounding Communities
Dr. DePalma proudly serves patients from Scottsdale, Phoenix and nearby areas, offering compassionate, expert care that combines modern medicine with personalized psychiatric support.
Transformative Mental Health Care in Phoenix & Scottsdale & Phoenix
If you’re in the Scottsdale Phoenix area and struggling with treatment-resistant depression or trauma, Ketamine therapy under the guidance of Dr. DePalma offers a rare and comprehensive path to healing. With his expertise as a Board-Certified Psychiatrist, you’ll receive not only the benefits of Ketamine but also the full spectrum of psychiatric care you deserve.
Your mental health journey can start today—because lasting change is possible.
FOR THOSE INTERESTED IN SOME KEY STUDIES DONE ON KETAMINE FOR THESE PURPOSES:
1. Murrough et al. (2013)
Title: Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial
Journal: American Journal of Psychiatry, 170(10), 1134–1142
DOI: 10.1176/appi.ajp.2013.13030392
2. Chilukuri et al. (2014)
Title: Acute antidepressant effects of intramuscular ketamine equivalent to intravenous ketamine
DOI: 10.4103/0253-7176.127258
3. Phillips et al. (2019)
Title: Single, repeated, and maintenance ketamine infusions for treatment-resistant depression: A systematic review and meta-analysis
Journal: Journal of Affective Disorders, 243, 486–495
DOI: 10.1016/j.jad.2018.10.003
4. Harihar et al. (2013)
Title: Intramuscular ketamine in acute depression: case reports
DOI: 10.4103/0253-7176.116251
Design: Case report describing intramuscular ketamine administration (0.5 mg/kg) in patients with severe depression, with repeat dosing and short-term clinical follow-up
Findings: IM ketamine produced rapid antidepressant effects within hours, with clinically meaningful symptom improvement sustained over subsequent days to weeks during follow-up. The report supported feasibility of IM administration as an alternative to IV ketamine for rapid symptom relief, though durability remained limited and required repeat dosing.
5. Shiroma et al. (2014)
Title: A randomized, double-blind, placebo-controlled trial of repeated ketamine infusions for treatment-resistant depression
Journal: Biological Psychiatry, 77(3), 181–190
DOI: 10.1016/j.biopsych.2014.01.028
6. Singh et al. (2016)
Title: A double-blind, randomized, placebo-controlled, dose-frequency study of intravenous ketamine in patients with treatment-resistant depression
Journal: American Journal of Psychiatry, 173(8), 816–826
DOI: 10.1176/appi.ajp.2016.16010037
7. Grabski et al. (2022)
Title: Adjunctive ketamine with relapse prevention–based psychological therapy in the treatment of alcohol use disorder
Journal: American Journal of Psychiatry, 179(2), 152–162
DOI: 10.1176/appi.ajp.2021.21030277
Design: Double-blind, randomized, placebo-controlled phase II trial comparing three IV ketamine infusions (0.8 mg/kg) plus psychological therapy vs. placebo conditions in recently detoxified patients with severe alcohol use disorder.
Findings: Ketamine groups demonstrated significantly greater percentage of days abstinent and reduced relapse risk over 6-month follow-up, with the strongest effects observed when ketamine was combined with structured relapse-prevention psychotherapy.
8. Dakwar et al. (2019)
Title: A single ketamine infusion combined with motivational enhancement therapy for alcohol dependence: A randomized midazolam-controlled pilot trial
Journal: American Journal of Psychiatry, 176(11), 923–930
DOI: 10.1176/appi.ajp.2019.18101174
Design: Randomized, double-blind pilot study comparing a single IV ketamine infusion vs. midazolam control, both combined with motivational enhancement therapy in alcohol-dependent individuals.
Findings: Ketamine was associated with increased abstinence rates and delayed relapse, with reductions in alcohol craving and sustained clinical benefit for several weeks following treatment.
9. Walsh et al. (2023)
Title: Ketamine treatment for alcohol use disorder: A systematic review
Journal: Frontiers in Psychiatry, 14, 1156007
DOI: 10.3389/fpsyt.2023.1156007
Design: Systematic review of clinical studies evaluating ketamine for alcohol use disorder, including randomized trials, cohort studies, and open-label investigations.
Findings: Across studies, ketamine was associated with reduced alcohol consumption, decreased craving, and increased abstinence duration, particularly when administered alongside structured psychotherapy interventions.
Title: Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial
Journal: American Journal of Psychiatry, 170(10), 1134–1142
DOI: 10.1176/appi.ajp.2013.13030392
- Design: Repeated ketamine infusions (6 doses over 2 weeks)
- Findings: Patients receiving multiple infusions had more robust and sustained reductions in depression scores than those receiving a single dose. At day 28, 70.8% of ketamine-treated patients were still classified as responders (vs. 15.4% for midazolam).
2. Chilukuri et al. (2014)
Title: Acute antidepressant effects of intramuscular ketamine equivalent to intravenous ketamine
DOI: 10.4103/0253-7176.127258
- Design: Randomized controlled comparison of intramuscular vs intravenous ketamine (single sub-anesthetic dose) in patients with depression
- Findings: Both IM and IV ketamine produced rapid and significant reductions in depressive symptoms within hours to days, with comparable short-term antidepressant efficacy. Symptom improvement was sustained at early follow-up (several days), supporting IM administration as a clinically viable alternative route for rapid antidepressant effect.
3. Phillips et al. (2019)
Title: Single, repeated, and maintenance ketamine infusions for treatment-resistant depression: A systematic review and meta-analysis
Journal: Journal of Affective Disorders, 243, 486–495
DOI: 10.1016/j.jad.2018.10.003
- Type: Meta-analysis of 11 studies (IV ketamine)
- Conclusion: Repeated ketamine infusions (4–6 sessions) led to higher response rates and longer-lasting antidepressant effects, with many patients maintaining benefit for 2–4 weeks post-treatment.
- Quote from paper:
“Durability of antidepressant response was consistently greater in studies that used repeated infusions compared to single-dose studies.”
4. Harihar et al. (2013)
Title: Intramuscular ketamine in acute depression: case reports
DOI: 10.4103/0253-7176.116251
Design: Case report describing intramuscular ketamine administration (0.5 mg/kg) in patients with severe depression, with repeat dosing and short-term clinical follow-up
Findings: IM ketamine produced rapid antidepressant effects within hours, with clinically meaningful symptom improvement sustained over subsequent days to weeks during follow-up. The report supported feasibility of IM administration as an alternative to IV ketamine for rapid symptom relief, though durability remained limited and required repeat dosing.
5. Shiroma et al. (2014)
Title: A randomized, double-blind, placebo-controlled trial of repeated ketamine infusions for treatment-resistant depression
Journal: Biological Psychiatry, 77(3), 181–190
DOI: 10.1016/j.biopsych.2014.01.028
- Design: 6 ketamine infusions (0.5 mg/kg IV) over 12 days
- Findings: Response rates increased over the treatment course, and antidepressant effects were sustained at day 14 and beyond in many responders.
- Quote from paper:
“Patients receiving repeated ketamine infusions showed a sustained antidepressant response through the 2-week follow-up period.”
6. Singh et al. (2016)
Title: A double-blind, randomized, placebo-controlled, dose-frequency study of intravenous ketamine in patients with treatment-resistant depression
Journal: American Journal of Psychiatry, 173(8), 816–826
DOI: 10.1176/appi.ajp.2016.16010037
- Design: Compared 2x/week vs. 3x/week dosing over 2 weeks (6 total sessions)
- Findings: Greater response durability in patients who received more frequent sessions, with antidepressant effects persisting through day 28 in many cases.
7. Grabski et al. (2022)
Title: Adjunctive ketamine with relapse prevention–based psychological therapy in the treatment of alcohol use disorder
Journal: American Journal of Psychiatry, 179(2), 152–162
DOI: 10.1176/appi.ajp.2021.21030277
Design: Double-blind, randomized, placebo-controlled phase II trial comparing three IV ketamine infusions (0.8 mg/kg) plus psychological therapy vs. placebo conditions in recently detoxified patients with severe alcohol use disorder.
Findings: Ketamine groups demonstrated significantly greater percentage of days abstinent and reduced relapse risk over 6-month follow-up, with the strongest effects observed when ketamine was combined with structured relapse-prevention psychotherapy.
8. Dakwar et al. (2019)
Title: A single ketamine infusion combined with motivational enhancement therapy for alcohol dependence: A randomized midazolam-controlled pilot trial
Journal: American Journal of Psychiatry, 176(11), 923–930
DOI: 10.1176/appi.ajp.2019.18101174
Design: Randomized, double-blind pilot study comparing a single IV ketamine infusion vs. midazolam control, both combined with motivational enhancement therapy in alcohol-dependent individuals.
Findings: Ketamine was associated with increased abstinence rates and delayed relapse, with reductions in alcohol craving and sustained clinical benefit for several weeks following treatment.
9. Walsh et al. (2023)
Title: Ketamine treatment for alcohol use disorder: A systematic review
Journal: Frontiers in Psychiatry, 14, 1156007
DOI: 10.3389/fpsyt.2023.1156007
Design: Systematic review of clinical studies evaluating ketamine for alcohol use disorder, including randomized trials, cohort studies, and open-label investigations.
Findings: Across studies, ketamine was associated with reduced alcohol consumption, decreased craving, and increased abstinence duration, particularly when administered alongside structured psychotherapy interventions.